Topinformationen

2020

Elpers, L., and Hensel, M. (2020). Expression and functional characterization of various chaperon-usher fimbriae, Curli fimbriae, and Type 4 Pili of Enterohemorrhagic Escherichia coli O157:H7 Sakai. Frontiers in Microbiology 11. 10.3389/fmicb.2020.00378

Elpers, L., Kretzschmar, J., Nuccio, S.P., Bäumler, A.J., and Hensel, M. (2020). Factors Required for Adhesion of Salmonella enterica Serovar Typhimurium to Corn Salad (Valerianella locusta). Appl Environ Microbiol 86. 10.1128/AEM.02757-19

Galeev, A., Suwandi, A., Bakker, H., Oktiviyari, A., Routier, F.H., Krone, L., Hensel, M., and Grassl, G.A. (2020). Proteoglycan-dependent endo-lysosomal fusion affects intracellular survival of Salmonella Typhimurium in epithelial cells. Frontiers in Immunology. In press.

Göser, V., and Hensel, M. (2020). Self-labeling enzyme tags for translocation analyses of Salmonella effector proteins. Methods Mol Biol in press.

Göser, V., Kehl, A., Roder, J., and Hensel, M. (2020). Role of the ESCRT-III complex in controlling integrity of the Salmonella-containing vacuole. Cell Microbiol e13176. 10.1111/cmi.13176

Kehl, A., Noster, J., and Hensel., M. (2020). Eat in or take out? Metabolism of intracellular Salmonella enterica. Trends Microbiol in press.

Klingl, S., Kordes, S., Schmid, B., Gerlach, R.G., Hensel, M., and Muller, Y.A. (2020). Recombinant protein production and purification of SiiD, SiiE and SiiF - Components of the SPI4-encoded type I secretion system from Salmonella Typhimurium. Protein Expr Purif, 105632. 10.1016/j.pep.2020.105632

Kommnick, C., and Hensel, M. (2020). Correlative light and scanning electron microscopy for adhesion/invasion studies of Salmonella Typhimurium in polarized monolayer cells. Meth Mol Biol in press.

2019

Göser, V., Kommnick, C., Liss, V., and Hensel, M. (2019). Self-labeling enzyme tags for analyses of translocation of Type III Secretion System effector proteins. MBio 10. 10.1128/mBio.00769-19

Kirchweger, P., Weiler, S., Egerer-Sieber, C., Blasl, A.T., Hoffmann, S., Schmidt, C., Sander, N., Merker, D., Gerlach, R.G., Hensel, M., et al. (2019). Structural and functional characterization of SiiA, an auxiliary protein from the SPI4-encoded type 1 secretion system from Salmonella enterica. Mol Microbiol 112, 1403-1422. 10.1111/mmi.14368

Kommnick, C., Lepper, A., and Hensel, M. (2019). Correlative light and scanning electron microscopy (CLSEM) for analysis of bacterial infection of polarized epithelial cells. Sci Rep 9, 17079. 10.1038/s41598-019-53085-6

Noster, J., Chao, T.C., Sander, N., Schulte, M., Reuter, T., Hansmeier, N., and Hensel, M. (2019). Proteomics of intracellular Salmonella enterica reveals roles of Salmonella pathogenicity island 2 in metabolism and antioxidant defense. PLoS Pathog 15, e1007741. 10.1371/journal.ppat.1007741

Noster, J., Hansmeier, N., Persicke, M., Chao, T.C., Kurre, R., Popp, J., Liss, V., Reuter, T., and Hensel, M. (2019). Blocks in tricarboxylic acid cycle of Salmonella enterica cause global perturbation of carbon storage, motility, and host-pathogen interaction. mSphere 4. 10.1128/mSphere.00796-19

Noster, J., Persicke, M., Chao, T.C., Krone, L., Heppner, B., Hensel, M., and Hansmeier, N. (2019). Impact of ROS-induced famage of TCA cvcle rnzymes on metabolism and Vvrulence of Salmonella enterica serovar Typhimurium. Front Microbiol 10, 762. 10.3389/fmicb.2019.00762

Röder, J., and Hensel, M. (2019). Presence of SopE and mode of infection result in increased Salmonella-containing vacuole damage and cytosolic release during host cell infection by Salmonella enterica. Cell Microbiol, e13155. 10.1111/cmi.13155

Schulte, M., Sterzenbach, T., Miskiewicz, K., Elpers, L., Hensel, M., and Hansmeier, N. (2019). A versatile remote control system for functional expression of bacterial virulence genes based on the tetA promoter. Int J Med Microbiol 309, 54-65. 10.1016/j.ijmm.2018.11.001

Suwandi, A., Galeev, A., Riedel, R., Sharma, S., Seeger, K., Sterzenbach, T., Garcia Pastor, L., Boyle, E.C., Gal-Mor, O., Hensel, M., et al. (2019). Std fimbriae-fucose interaction increases Salmonella-induced intestinal inflammation and prolongs colonization. PLoS Pathog 15, e1007915. 10.1371/journal.ppat.1007915

2018

Brink, T., Leiss, V., Siegert, P., Jehle, D., Ebner, J.K., Schwan, C., Shymanets, A., Wiese, S., Nurnberg, B., Hensel, M., et al. (2018). Salmonella Typhimurium effector SseI inhibits chemotaxis and increases host cell survival by deamidation of heterotrimeric Gi proteins. PLoS Pathog 14, e1007248. 10.1371/journal.ppat.1007248

Fulde, M., Sommer, F., Chassaing, B., van Vorst, K., Dupont, A., Hensel, M., Basic, M., Klopfleisch, R., Rosenstiel, P., Bleich, A., et al. (2018). Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition. Nature 560, 489-493. 10.1038/s41586-018-0395-5

Haas, A., Hensel, M., Luhrmann, A., Rudel, T., Saftig, P., and Schaible, U.E. (2018). Intracellular compartments of pathogens: Highways to hell or stairways to heaven? Int J Med Microbiol 308, 1-2. 10.1016/j.ijmm.2017.10.009

Namakchian, M., Kassler, K., Sticht, H., Hensel, M., and Deiwick, J. (2018). Structure-based functional analysis of effector protein SifA in living cells reveals motifs important for Salmonella intracellular proliferation. Int J Med Microbiol 308, 84-96. 10.1016/j.ijmm.2017.09.004

Sprenger, M., Kasper, L., Hensel, M., and Hube, B. (2018). Metabolic adaptation of intracellular bacteria and fungi to macrophages. Int J Med Microbiol 308, 215-227. 10.1016/j.ijmm.2017.11.001

Zhang, K., Riba, A., Nietschke, M., Torow, N., Repnik, U., Putz, A., Fulde, M., Dupont, A., Hensel, M., and Hornef, M. (2018). Minimal SPI1-T3SS effector requirement for Salmonella enterocyte invasion and intracellular proliferation in vivo. PLoS Pathog 14, e1006925. 10.1371/journal.ppat.1006925

2017

Aviv, G., Elpers, L., Mikhlin, S., Cohen, H., Vitman Zilber, S., Grassl, G.A., Rahav, G., Hensel, M., and Gal-Mor, O. (2017). The plasmid-encoded Ipf and Klf fimbriae display different expression and varying roles in the virulence of Salmonella enterica serovar Infantis in mouse vs. avian hosts. PLoS Pathog 13, e1006559.

Fabiani, F.D., Renault, T.T., Peters, B., Dietsche, T., Galvez, E.J.C., Guse, A., Freier, K., Charpentier, E., Strowig, T., Franz-Wachtel, M., et al. (2017). A flagellum-specific chaperone facilitates assembly of the core type III export apparatus of the bacterial flagellum. PLoS Biol 15, e2002267.

Hansmeier, N., Miskiewicz, K., Elpers, L., Liss, V., Hensel, M., and Sterzenbach, T. (2017). Functional expression of the entire adhesiome of Salmonella enterica serotype Typhimurium. Sci Rep 7, 10326. Download

Liss, V., Swart, A.L., Kehl, A., Hermanns, N., Zhang, Y., Chikkaballi, D., Bohles, N., Deiwick, J., and Hensel, M. (2017). Salmonella enterica remodels the host cell endosomal system for efficient intravacuolar nutrition. Cell Host Microbe 21, 390-402.

Peters, B., Stein, J., Klingl, S., Sander, N., Sandmann, A., Taccardi, N., Sticht, H., Gerlach, R.G., Muller, Y.A., and Hensel, M. (2017). Structural and functional dissection reveals distinct roles of Ca2+-binding sites in the giant adhesin SiiE of Salmonella enterica. PLoS Pathog 13, e1006418.

2016

Barlag, B., Beutel, O., Janning, D., Czarniak, F., Richter, C.P., Kommnick, C., Goser, V., Kurre, R., Fabiani, F., Erhardt, M., et al. (2016). Single molecule super-resolution imaging of proteins in living Salmonella enterica using self-labelling enzymes. Sci Rep 6, 31601.

Klionsky, D.J., Abdelmohsen, K., Abe, A., Abedin, M.J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C.M., Adams, P.D., Adeli, K., et al. (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12, 1-222.

Ortiz de Orue Lucana, D., Hickey, N., Hensel, M., Klare, J.P., Geremia, S., Tiufiakova, T., and Torda, A.E. (2016). The Crystal Structure of the C-Terminal Domain of the Salmonella enterica PduO Protein: An Old Fold with a New Heme-Binding Mode. Front Microbiol 7, 1010.

Schulte, M., and Hensel, M. (2016). Models of intestinal infection by Salmonella enterica: introduction of a new neonate mouse model. F1000Res 5.

2015

Barlag, B., and Hensel, M. (2015). The giant adhesin SiiE of Salmonella enterica. Molecules 20, 1134-1150.

Czarniak, F., and Hensel, M. (2015). Red-mediated recombineering of Salmonella enterica genomes. Methods Mol Biol 1225, 63-79.

Frahm, M., Felgner, S., Kocijancic, D., Rohde, M., Hensel, M., Curtiss, R., 3rd, Erhardt, M., and Weiss, S. (2015). Efficiency of conditionally attenuated Salmonella enterica serovar Typhimurium in bacterium-mediated tumor therapy. MBio 6.

Hegazy, W.A., Xu, X., Metelitsa, L., and Hensel, M. (2015). Correction for Hegazy et al., Evaluation of Salmonella enterica type III secretion system effector proteins as carriers for heterologous vaccine antigens. Infect Immun 83, 1225.

Herweg, J.A., Hansmeier, N., Otto, A., Geffken, A.C., Subbarayal, P., Prusty, B.K., Becher, D., Hensel, M., Schaible, U.E., Rudel, T., et al. (2015). Purification and proteomics of pathogen-modified vacuoles and membranes. Front Cell Infect Microbiol 5, 48.

Jennewein, J., Matuszak, J., Walter, S., Felmy, B., Gendera, K., Schatz, V., Nowottny, M., Liebsch, G., Hensel, M., Hardt, W.D., et al. (2015). Low-oxygen tensions found in Salmonella-infected gut tissue boost Salmonella replication in macrophages by impairing antimicrobial activity and augmenting Salmonella virulence. Cell Microbiol 17, 1833-1847.

Kehl, A., and Hensel, M. (2015). Live cell imaging of intracellular Salmonella enterica. Methods Mol Biol 1225, 199-225.

Liss, V., Barlag, B., Nietschke, M., and Hensel, M. (2015). Self-labelling enzymes as universal tags for fluorescence microscopy, super-resolution microscopy and electron microscopy. Sci Rep 5, 17740.

Liss, V., and Hensel, M. (2015). Take the tube: remodelling of the endosomal system by intracellular Salmonella enterica. Cell Microbiol 17, 639-647.

Popp, J., Noster, J., Busch, K., Kehl, A., Zur Hellen, G., and Hensel, M. (2015). Role of host cell-derived amino acids in nutrition of intracellular Salmonella enterica. Infect Immun 83, 4466-4475.

Vorwerk, S., Krieger, V., Deiwick, J., Hensel, M., and Hansmeier, N. (2015). Proteomes of host cell membranes modified by intracellular activities of Salmonella enterica. Mol Cell Proteomics 14, 81-92.

Wille, T., Barlag, B., Jakovljevic, V., Hensel, M., Sourjik, V., and Gerlach, R.G. (2015). A gateway-based system for fast evaluation of protein-protein interactions in bacteria. PLoS One 10, e0123646.

Zhang, Y.Y., Krieger, V., and Hensel, M. (2015). Application of fluorescent nanoparticles to study remodeling of the endolysosomal system by intracellular bacteria. JOVE-Journal of Visualized Experiments 95, e52048.

2014

Ahmed, Z., Zeeshan, S., Huber, C., Hensel, M., Schomburg, D., Munch, R., Eylert, E., Eisenreich, W., and Dandekar, T. (2014). 'Isotopo' a database application for facile analysis and management of mass isotopomer data. Database (Oxford) 2014.

Böhles, N., Busch, K., and Hensel, M. (2014). Vaccines against human diarrheal pathogens: Current status and perspectives. Hum Vaccin Immunother 10, 1522-1535.

Czarniak, F., and Hensel, M. (2014). Red-Mediated Recombineering of Salmonella enterica Genomes. Methods Mol Biol 1225, 63-79.

Grin, I., Hartmann, M.D., Sauer, G., Hernandez Alvarez, B., Schutz, M., Wagner, S., Madlung, J., Macek, B., Felipe-Lopez, A., Hensel, M., et al. (2014). A trimeric lipoprotein assists in trimeric autotransporter biogenesis in enterobacteria. J Biol Chem 289, 7388-7398.

Husseiny, M.I., Rawson, J., Kaye, A., Nair, I., Todorov, I., Hensel, M., Kandeel, F., and Ferreri, K. (2014). An oral vaccine for type 1 diabetes based on live attenuated Salmonella. Vaccine 32, 2300-2307.

Kehl, A., and Hensel, M. (2014). Live Cell Imaging of Intracellular Salmonella enterica. Methods Mol Biol 1225, 199-225.

Krieger, V., Liebl, D., Zhang, Y., Rajashekar, R., Chlanda, P., Giesker, K., Chikkaballi, D., and Hensel, M. (2014). Reorganization of the endosomal system in Salmonella-infected cells: the ultrastructure of Salmonella-induced tubular compartments. PLoS Pathog 10, e1004374.

Lorkowski, M., Felipe-Lopez, A., Danzer, C.A., Hansmeier, N., and Hensel, M. (2014). Salmonella enterica invasion of polarized epithelial cells is a highly cooperative effort. Infect Immun 82, 2657-2667.

Rajashekar, R., Liebl, D., Chikkaballi, D., Liss, V., and Hensel, M. (2014). Live Cell Imaging Reveals Novel Functions of Salmonella enterica SPI2-T3SS Effector Proteins in Remodeling of the Host Cell Endosomal System. PLoS One 9, e115423.

Wagner, C., Barlag, B., Gerlach, R.G., Deiwick, J., and Hensel, M. (2014). The Salmonella enterica giant adhesin SiiE binds to polarized epithelial cells in a lectin-like manner. Cell Microbiol 16, 962-975.

Wille, T., Wagner, C., Mittelstadt, W., Blank, K., Sommer, E., Malengo, G., Dohler, D., Lange, A., Sourjik, V., Hensel, M., et al. (2014). SiiA and SiiB are novel type I secretion system subunits controlling SPI4-mediated adhesion of Salmonella enterica. Cell Microbiol 16, 161-178.

Xu, X., Hegazy, W.A., Guo, L., Gao, X., Courtney, A.N., Kurbanov, S., Liu, D., Tian, G., Manuel, E.R., Diamond, D.J., et al. (2014). Effective cancer vaccine platform based on attenuated Salmonella and a type III secretion system. Cancer Res 74, 6260-6270.

Zhang, K., Dupont, A., Torow, N., Gohde, F., Leschner, S., Lienenklaus, S., Weiss, S., Brinkmann, M.M., Kuhnel, M., Hensel, M., et al. (2014). Age-dependent enterocyte invasion and microcolony formation by Salmonella. PLoS Pathog 10, e1004385.

2013

Ahmed, Z., Zeeshan, S., Huber, C., Hensel, M., Schomburg, D., Munch, R., Eisenreich, W., and Dandekar, T. (2013). Software LS-MIDA for efficient mass isotopomer distribution analysis in metabolic modelling. BMC Bioinformatics 14, 218.

Griessl, M.H., Schmid, B., Kassler, K., Braunsmann, C., Ritter, R., Barlag, B., Stierhof, Y.D., Sturm, K.U., Danzer, C., Wagner, C., et al. (2013). Structural insight into the giant Ca(2)(+)-binding adhesin SiiE: implications for the adhesion of Salmonella enterica to polarized epithelial cells. Structure 21, 741-752.

Hensel, M., Klingauf, J., and Piehler, J. (2013). Imaging the invisible: resolving cellular microcompartments by superresolution microscopy techniques. Biol Chem 394, 1097-1113.

Zhang, Y., and Hensel, M. (2013). Evaluation of nanoparticles as endocytic tracers in cellular microbiology. Nanoscale 5, 9296-9309.

2012

Dandekar, T., Astrid, F., Jasmin, P., and Hensel, M. (2012). Salmonella enterica: a surprisingly well-adapted intracellular lifestyle. Front Microbiol 3, 164.

Hegazy, W.A., and Hensel, M. (2012). Salmonella enterica as a vaccine carrier. Future Microbiol 7, 111-127.

Hegazy, W.A., Xu, X., Metelitsa, L., and Hensel, M. (2012). Evaluation of Salmonella enterica type III secretion system effector proteins as carriers for heterologous vaccine antigens. Infect Immun 80, 1193-1202.

Hölzer, S.U., and Hensel, M. (2012). Divergent roles of Salmonella pathogenicity island 2 and metabolic traits during interaction of S. enterica serovar typhimurium with host cells. PLoS One 7, e33220.

Muller, P., Chikkaballi, D., and Hensel, M. (2012). Functional dissection of SseF, a membrane-integral effector protein of intracellular Salmonella enterica. PLoS One 7, e35004.

Swart, A.L., and Hensel, M. (2012). Interactions of Salmonella enterica with dendritic cells. Virulence 3, 660-667.

Ustun, S., Muller, P., Palmisano, R., Hensel, M., and Bornke, F. (2012). SseF, a type III effector protein from the mammalian pathogen Salmonella enterica, requires resistance-gene-mediated signalling to activate cell death in the model plant Nicotiana benthamiana. New Phytol 194, 1046-1060.

Wiese, M., Gerlach, R.G., Popp, I., Matuszak, J., Mahapatro, M., Castiglione, K., Chakravortty, D., Willam, C., Hensel, M., Bogdan, C., et al. (2012). Hypoxia-mediated impairment of the mitochondrial respiratory chain inhibits the bactericidal activity of macrophages. Infect Immun 80, 1455-1466.

2011

Blank K, Hensel M, Gerlach RG (2011).Rapid and highly efficient method for scarless mutagenesis within the Salmonella enterica chromosome. PLoS One, 6, e15763.

Creuzburg, K., Heeren, S., Lis, C.M., Kranz, M., Hensel, M., and Schmidt, H. (2011) Genetic background and mobility of variants of the gene nleA in attaching and effacing Escherichia coli. Appl. Environ. Microbiol. 77, 8705-8713.

Crull, K., Rohde, M., Westphal, K., Loessner, H., Wolf, K., Felipe-López, A., Hensel, M., Weiss, S. (2011) Biofilm formation by Salmonella enterica serovar Typhimurium colonizing solid tumors. Cell. Microbiol. 13, 1223-1233.

Held, C., Palmisano, R., Dach, C., Hensel, M. and Wittenberg, T. (2011) Parameter-adapted automated segmentation of fluorescence microscopy images. Cytometry A. 79, 933-945.

Jantsch, J., Wiese, M., Castiglione, K., Schödel, J., Gläsner, J, Kolbe, S., Schleicher, U., Eckardt, K.-U., Hensel, H., Lang, R., Bogdan, C., Schnare, M. and Willam, C. (2011) Toll-like receptor activation and hypoxia use distinct signalling pathways to stabilize HIF-1 and result in differential gene expression. J. Leukoc. Biol. 90, 551-562.

Jantsch, J, Chikkaballi, D. and Hensel, M. (2011) Cellular aspects of immunity to intracellular Salmonella enterica. Immunol. Rev. 240, 185-195.

Manuel, E.R., Blache, C.A., Paquette, R., Kaltcheva, T.I., Ellenhorn, J.D.I., Hensel, M., Metelitsa, L., and Diamond, D.J. (2011) Enhancement of cancer vaccine therapy by systemic delivery of a tumor-targeting Salmonella-based STAT3 shRNA suppresses the growth of established melanoma tumors. Cancer Res. 71:4183-4191.

Rajashekar, R. and Hensel, M. (2011) Dynamic modification of microtubule-dependent transport by effector proteins of intracellular Salmonella enterica. Eur. J. Cell Biol. 90, 897-902.

Schwidder, M. Hensel, M., Schmidt, H. (2011). Regulation of nleA in Shiga toxin-producing Escherichia coli O84:H4 2 strain 4795/97. J. Bacteriol., 193, 832-841.

Sturm, K.U., Griessl, M.A., Wagner, C., Deiwick, J., Hensel, M., and Muller, Y.A. (2011) Crystallization and preliminary crystallographic analysis of an Ig-domain-encompassing fragment of the giant adhesion protein SiiE from Salmonella enterica. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 67, 1371-1374.

Wagner, C., Polke, M., Gerlach, R.G., Linke, D., Stierhof, Y.D., Schwarz, H., Hensel, M. (2011) Functional and molecular dissection of SiiE, a giant non-fimbrial adhesin of Salmonella enterica. Cell. Microbiol. 13, 1236-1301.

2010

Hölzer, S.U. and Hensel, M. (2010) Functional dissection of translocon proteins of the Salmonella Pathogenicity Island 2-encoded type III secretion system. BMC Microbiol., 10, 104.

Ott, L., Höller, M., Rheinlaender, J., Schäffer, T.E., Hensel, M. and Burkovski, A. (2010) Strain-specific differences in the interaction of Corynebacterium diphtheriae with host cells. BMC Microbiol., 10, 257.

Ott, L., Höller, M., Gerlach, R.G., Hensel, M., Rheinlaender, J., Schaffer, T.E., and Burkovski, A. (2010). Corynebacterium diphtheriae invasion-associated protein (DIP1281) is involved in cell surface organization, adhesion and internalization in epithelial cells. BMC Microbiol 10, 2.
Download

Wiese, M., Castiglione, K., Hensel, M., Schleicher, U., Bogdan, C., and Jantsch, J. (2010). Small interfering RNA (siRNA) delivery into murine bone marrow-derived macrophages by electroporation. J Immunol Methods 353, 102-110.
Download

Xu, X., and Hensel, M. (2010). Systematic analysis of the SsrAB virulon of Salmonella enterica. Infect Immun 78, 49-58.
Download

Xu, X., Husseiny, M. I., Goldwich, A., and Hensel, M. (2010). Efficacy of intracellular activated promoters for generation of Salmonella-based vaccines. Infect. Immun., 78, 4828-4838.

2009

Duerr, C.U., Zenk, S.F., Chassin, C., Pott, J., Gutle, D., Hensel, M., and Hornef, M.W. (2009). O-antigen delays lipopolysaccharide recognition and impairs antibacterial host defense in murine intestinal epithelial cells. PLoS Pathogens 5, e1000567.
Download

Gerlach, R.G., Jäckel, D., Holzer, S.U., and Hensel, M. (2009). Rapid oligonucleotide-based recombineering of the chromosome of Salmonella enterica. Appl Environ Microbiol 75, 1575-1580.
Download

Hölzer, S.U., Schlumberger, M.C., Jäckel, D., and Hensel, M. (2009). Effect of the O-antigen length of lipopolysaccharide on the functions of Type III secretion systems in Salmonella enterica. Infect Immun 77, 5458-5470.
Download

Husseiny, M.I., and Hensel, M. (2009). Evaluation of Salmonella live vaccines with chromosomal expression cassettes for translocated fusion proteins. Vaccine 27, 3780-3787.
Download

Xiong, G., Husseiny, M.I., Song, L., Erdreich-Epstein, A., Shackleford, G.M., Seeger, R.C., Jäckel, D., Hensel, M., and Metelitsa, L.S. (2009). Novel cancer vaccine based on genes of Salmonella pathogenicity Island 2. Int J Cancer 126, 2622-2634.

Zenk, S.F., Jantsch, J., and Hensel, M. (2009). Role of Salmonella enterica lipopolysaccharide in activation of dendritic cell functions and bacterial containment. J Immunol 183, 2697-2707.
Download

2008

Cheminay, C., and Hensel, M. (2008). Rational design of Salmonella recombinant vaccines. Int J Med Microbiol 298, 87-98.
Download

Eswarappa, S.M., Panguluri, K.K., Hensel, M., and Chakravortty, D. (2008). The yejABEF operon of Salmonella confers resistance to antimicrobial peptides and contributes to its virulence. Microbiology 154, 666-678.
Download

Gerlach, R.G., Claudio, N., Rohde, M., Jäckel, D., Wagner, C., and Hensel, M. (2008). Cooperation of Salmonella pathogenicity islands 1 and 4 is required to breach epithelial barriers. Cell Microbiol 10, 2364-2376.
Download
Supplemental Material Download  

Halici, S., Zenk, S.F., Jantsch, J., and Hensel, M. (2008). Functional analysis of the Salmonella Pathogenicity Island 2-mediated inhibition of antigen presentation in dendritic cells. Infect Immun 76, 4924-4933.
Download

Husseiny, M.I., and Hensel, M. (2008). Construction of highly attenuated Salmonella enterica serovar Typhimurium live vectors for delivering heterologous antigens by chromosomal integration. Microbiol Res 163, 605-615.
Download

Jantsch, J., Chakravortty, D., Turza, N., Prechtel, A.T., Buchholz, B., Gerlach, R.G., Volke, M., Glasner, J., Warnecke, C., Wiesener, M.S., et al. (2008). Hypoxia and Hypoxia-Inducible Factor-1{alpha} modulate lipopolysaccharide-induced dendritic cell activation and function. J Immunol 180, 4697-4705.
Download

Jantsch, J., Turza, N., Volke, M., Eckardt, K.U., Hensel, M., Steinkasserer, A., Willam, C., and Prechtel, A.T. (2008). Small interfering RNA (siRNA) delivery into murine bone marrow-derived dendritic cells by electroporation. J Immunol Methods 337, 71-77.
Download

Rajashekar, R., Liebl, D., Seitz, A., and Hensel, M. (2008). Dynamic remodeling of the endosomal system during formation of Salmonella-induced filaments by intracellular Salmonella enterica. Traffic 9, 2100-2116.
Download
Supplemental Material Download

2007

Gerlach, R.G., Hölzer, S.U., Jäckel, D., and Hensel, M. (2007). Rapid engineering of bacterial reporter gene fusions by using Red recombination. Appl Environ Microbiol 73, 4234-4242.
Download

Gerlach, R.G., Jäckel, D., Geymeier, N., and Hensel, M. (2007). Salmonella pathogenicity island 4-mediated adhesion is coregulated with invasion genes in Salmonella enterica. Infect Immun 75, 4697-4709.
Download

Gerlach, R.G., Jäckel, D., Stecher, B., Wagner, C., Lupas, L., Hardt, W.D., and Hensel, M. (2007). Salmonella Pathogenicity Island 4 encodes a giant non-fimbrial adhesin and the cognate type 1 secretion system. Cell Microbiol 9, 1834-1850.
Download
Supplemental Material Download

Gerlach, R.G., and Hensel, M. (2007). Protein secretion systems and adhesins: the molecular armory of Gram-negative pathogens. Int J Med Microbiol 297, 401-415.
Download

Gerlach, R.G., and Hensel, M. (2007). Salmonella pathogenicity islands in host specificity, host pathogen-interactions and antibiotics resistance of Salmonella enterica. Berl Munch Tierarztl Wochenschr 120, 317-327.
Download

Hensel, M. (2007). Genome-based identification and molecular analyses of pathogenicity islands and genomic islands in Salmonella enterica. Methods Mol Biol 394, 77-88.

Husseiny, M.I., Wartha, F., and Hensel, M. (2007). Recombinant vaccines based on translocated effector proteins of Salmonella Pathogenicity Island 2. Vaccine 25, 185-193.
Download

2006

Abrahams, G.L., and Hensel, M. (2006). Manipulating cellular transport and immune responses: dynamic interactions between intracellular Salmonella enterica and its host cells. Cell Microbiol 8, 728-737.
Download

Abrahams, G.L., Müller, P., and Hensel, M. (2006). Functional dissection of SseF, a type III effector protein involved in positioning the Salmonella-containing vacuole. Traffic 7, 950-965.
Download

Husseiny, M., Wartha, F., Hensel, M. (2006).Recombinant vaccines based on translocated effector proteins of Salmonella Pathogenicity Island 2, 185-93.
Download

Kuhle, V., Abrahams, G.L., and Hensel, M. (2006). Intracellular Salmonella enterica redirect exocytic transport processes in a Salmonella pathogenicity island 2-dependent manner. Traffic 7, 716-730.
Download

Löber, S., Jäckel, D., Kaiser, N., and Hensel, M. (2006). Regulation of Salmonella pathogenicity island 2 genes by independent environmental signals. Int J Med Microbiol 296, 435-447.
Download

2005

Chakravortty, D., Rohde, M., Jäger, L., Deiwick, J., and Hensel, M. (2005). Formation of a novel surface structure encoded by Salmonella Pathogenicity Island 2. EMBO J 24, 2043-2052.
Download

Cheminay, C., Möhlenbrink, A., and Hensel, M. (2005). Intracellular Salmonella inhibit antigen presentation by dendritic cells. J Immunol 174, 2892-2899.
Download

Creuzburg, K., Recktenwald, J., Kuhle, V., Herold, S., Hensel, M., and Schmidt, H. (2005). The Shiga toxin 1-converting bacteriophage BP-4795 encodes an NleA-like type III effector protein. J Bacteriol 187, 8494-8498.
Download

Hapfelmeier, S., Stecher, B., Barthel, M., Kremer, M., Muller, A.J., Heikenwalder, M., Stallmach, T., Hensel, M., Pfeffer, K., Akira, S., et al. (2005). The Salmonella pathogenicity island (SPI)-2 and SPI-1 type III secretion systems allow Salmonella serovar typhimurium to trigger colitis via MyD88-dependent and MyD88-independent mechanisms. J Immunol 174, 1675-1685.

Husseiny, M.I., and Hensel, M. (2005). Rapid method for the construction of Salmonella enterica Serovar Typhimurium vaccine carrier strains. Infect Immun 73, 1598-1605.
Download

Husseiny, M.I., and Hensel, M. (2005). Evaluation of an intracellular-activated promoter for the generation of live Salmonella recombinant vaccines. Vaccine 23, 2580-2590.
Download

Knodler, L.A., Bestor, A., Ma, C., Hansen-Wester, I., Hensel, M., Vallance, B.A., and Steele-Mortimer, O. (2005). Cloning vectors and fluorescent proteins can significantly inhibit Salmonella enterica virulence in both epithelial cells and macrophages: implications for bacterial pathogenesis studies. Infect Immun 73, 7027-7031.
Download

2004

Cheminay, C., Chakravortty, D., and Hensel, M. (2004). Role of neutrophils in murine salmonellosis. Infect Immun 72, 468-447.
Download

Hansen-Wester, I., Chakravortty, D., and Hensel, M. (2004). Functional transfer of Salmonella Pathogenicity Island 2 to Salmonella bongori and Escherichia coli. Infect Immun 72, 2879-2888.
Download

Hensel, M. (2004). Evolution of pathogenicity islands of Salmonella enterica. Int J Med Microbiol 294, 95-102.  
Download

Kuhle, V., Jäckel, D., and Hensel, M. (2004). Effector proteins encoded by Salmonella pathogenicity island 2 interfere with the microtubule cytoskeleton after translocation into host cells. Traffic 5, 356-370.

Kuhle, V., and Hensel, M. (2004). Cellular microbiology of intracellular Salmonella enterica: functions of the type III secretion system encoded by Salmonella pathogenicity island 2. Cell Mol Life Sci 61, 2812-2826.
Download

Schmidt, H., and Hensel, M. (2004). Pathogenicity islands in bacterial pathogenesis. Clin Microbiol Rev 17, 14-56.
Download

2003

Chakravortty, D., and Hensel, M. (2003). Inducible nitric oxide synthase and control of intracellular bacterial pathogens. Microbes Infect 5, 621-627.
Download

Jantsch, J., Cheminay, C., Chakravortty, D., Lindig, T., Hein, J., and Hensel, M. (2003). Intracellular activities of Salmonella enterica in murine dendritic cells. Cell Microbiol 5, 933-945.
Download

Knodler, L.A., Vallance, B.A., Hensel, M., Jäckel, D., Finlay, B.B., and Steele-Mortimer, O. (2003). Salmonella type III effectors PipB and PipB2 are targeted to detergent-resistant microdomains on internal host cell membranes. Mol Microbiol 49, 685-704.
Download

Rappl, C., Deiwick, J., and Hensel, M. (2003). Acidic pH is required for the functional assembly of the type III secretion system encoded by Salmonella pathogenicity island 2. FEMS Microbiol Lett 226, 363-372.
Download

2002

Chakravortty, D., Hansen-Wester, I., and Hensel, M. (2002). Salmonella pathogenicity island 2 mediates protection of intracellular Salmonella from reactive nitrogen intermediates. J Exp Med 195, 1155-1166.
Download

Cheminay, C., Schoen, M., Hensel, M., Wandersee-Steinhauser, A., Ritter, U., Körner, H., Röllinghoff, M., and Hein, J. (2002). Migration of Salmonella typhimurium-harboring bone marrow-derived dendritic cells towards the chemokines CCL19 and CCL21. Microb Pathog 32, 207-218.
Download

Deiwick, J., Rappl, C., Stender, S., Jungblut, P.R., and Hensel, M. (2002). Proteomic approaches to Salmonella Pathogenicity Island 2 encoded proteins and the SsrAB regulon. Proteomics 2, 792-799.
Download

Freeman, J.A., Rappl, C., Kuhle, V., Hensel, M., and Miller, S.I. (2002). SpiC is required for translocation of Salmonella Pathogenicity Island 2 effectors and secretion of translocon proteins SseB and SseC. J Bacteriol 184, 4971-4980.
Download

Hansen-Wester, I., and Hensel, M. (2002). Genome-based identification of chromosomal regions specific for Salmonella spp. Infect Immun 70, 2351-2360.
Download

Hansen-Wester, I., Stecher, B., and Hensel, M. (2002). Analyses of the evolutionary distribution of Salmonella translocated effectors. Infect Immun 70, 1619-1622.
Download

Hansen-Wester, I., Stecher, B., and Hensel, M. (2002). Type III secretion of Salmonella enterica serovar Typhimurium translocated effectors and SseFG. Infect Immun 70, 1403-1409.
Download

Kuhle, V., and Hensel, M. (2002). SseF and SseG are translocated effectors of the type III secretion system of Salmonella pathogenicity island 2 that modulate aggregation of endosomal compartments. Cell Microbiol 4, 813-824.
Download

Pawelek, J.M., Sodi, S., Chakraborty, A.K., Platt, J.T., Miller, S., Holden, D.W., Hensel, M., and Low, K.B. (2002). Salmonella pathogenicity island-2 and anticancer activity in mice. Cancer Gene Ther 9, 813-818.
Download

2001

Hansen-Wester, I., and Hensel, M. (2001). Salmonella pathogenicity islands encoding type III secretion systems. Microbes Infect 3, 549-559.
Download

Nikolaus, T., Deiwick, J., Rappl, C., Freeman, J.A., Schröder, W., Miller, S.I., and Hensel, M. (2001). SseBCD proteins are secreted by the type III secretion system of Salmonella pathogenicity island 2 and function as a translocon. J Bacteriol 183, 6036-6045.
Download

2000

Hensel, M. (2000). Salmonella pathogenicity island 2. Mol Microbiol 36, 1015-1023.
Download

1999

Beuzon, C.R., Banks, G., Deiwick, J., Hensel, M., and Holden, D.W. (1999). pH-dependent secretion of SseB, a product of the SPI-2 type III secretion system of Salmonella typhimurium. Mol Microbiol 33, 806-816.
Download

Deiwick, J., and Hensel, M. (1999). Regulation of virulence genes by environmental signals in Salmonella typhimurium. Electrophoresis 20, 813-817.
Download

Deiwick, J., Nikolaus, T., Erdogan, S., and Hensel, M. (1999). Environmental regulation of Salmonella pathogenicity island 2 gene expression. Mol Microbiol 31, 1759-1773.
Download

Hensel, M., Hinsley, A.P., Nikolaus, T., Sawers, G., and Berks, B.C. (1999). The genetic basis of tetrathionate respiration in Salmonella typhimurium. Mol Microbiol 32, 275-288.
Download

Hensel, M., Nikolaus, T., and Egelseer, C. (1999). Molecular and functional analysis indicates a mosaic structure of Salmonella pathogenicity island 2. Mol Microbiol 31, 489-498.
Download

Medina, E., Paglia, P., Nikolaus, T., Muller, A., Hensel, M., and Guzman, C.A. (1999). Pathogenicity island 2 mutants of Salmonella typhimurium are efficient carriers for heterologous antigens and enable modulation of immune responses. Infect Immun 67, 1093-1099.
Download

1998

Deiwick, J., Nikolaus, T., Shea, J.E., Gleeson, C., Holden, D.W., and Hensel, M. (1998). Mutations in Salmonella Pathogenicity Island 2 (SPI2) genes affecting transcription of SPI1 genes and resistance to antimicrobial agents. J Bacteriol 180, 4775-4780.
Download

Hensel, M. (1998). Whole genome scan for habitat-specific genes by signature-tagged mutagenesis. Electrophoresis 19, 608-612.

Hensel, M., Arst, H.N., Aufauvre Brown, A., and Holden, D.W. (1998). The role of the Aspergillus fumigatus areA gene in invasive pulmonary aspergillosis. MolGenGenet 258, 553-557.
Download

Hensel, M., Shea, J.E., Waterman, S.R., Mundy, R., Nikolaus, T., Banks, G., Vazquez-Torres, A., Gleeson, C., Fang, F., and Holden, D.W. (1998). Genes encoding putative effector proteins of the type III secretion system of Salmonella Pathogenicity Island 2 are required for bacterial virulence and proliferation in macrophages. Mol Microbiol 30, 163-174.
Download

Holden, D.W., Hensel, M., Williams, P., Ketley, J., and Salmond, G.P. (1998). Signature-tagged mutagenesis. In Bacterial Pathogenesis (London, Academic Press), pp. 359-369.

1997

Hensel, M., Shea, J.E., Bäumler, A.J., Gleeson, C., Blattner, F.R., and Holden, D.W. (1997). Analysis of the boundaries of Salmonella pathogenicity island 2 and the corresponding chromosomal region of Escherichia coli K-12. J Bacteriol 179, 1105-1111.
Download

Hensel, M., Shea, J.E., Raupach, B., Monack, D., Falkow, S., Gleeson, C., and Holden, D.W. (1997). Functional analysis of ssaJ and the ssaK/U operon, 13 genes encoding components of the type III secretion apparatus of Salmonella pathogenicity island 2. Mol Microbiol 24, 155-167.
Download

1996

Hensel, M., Achmus, H., Deckers Hebestreit, G., and Altendorf, K. (1996). The ATP synthase of Streptomyces lividans: characterization and purification of the F1Fo complex. Biochim Biophys Acta 1274, 101-108.

Hensel, M., and Holden, D.W. (1996). Molecular genetic approaches for the study of virulence in both pathogenic bacteria and fungi. Microbiology 142, 1049-1058.

Shea, J.E., Hensel, M., Gleeson, C., and Holden, D.W. (1996). Identification of a virulence locus encoding a second type III secretion system in Salmonella typhimurium. Proc Natl Acad Sci U S A 93, 2593-2597.
Download

1995

Hensel, M., Tang, C.M., Arst, H.N., Jr., and Holden, D.W. (1995). Regulation of fungal extracellular proteases and their role in mammalian pathogenesis. Can J Bot 73, 1065-1070.

Hensel, M., Shea, J.E., Gleeson, C., Jones, M.D., Dalton, E., and Holden, D.W. (1995). Simultaneous identification of bacterial virulence genes by negative selection. Science 269, 400-403.

Hensel, M., Lill, H., Schmid, R., Deckers-Hebestreit, G., and Altendorf, K. (1995). The ATP synthase (F1F0) of Streptomyces lividans: sequencing of the atp operon and phylogenetic considerations with subunit beta. Gene 152, 11-17.
Download

1991

Hensel, M., Deckers-Hebestreit, G., and Altendorf, K. (1991). Purification and characterization of the F1 portion of the ATP synthase (F1Fo) of Streptomyces lividans. Eur J Biochem 202, 1313-1319.

1990

Hensel, M., Deckers-Hebestreit, G., Schmid, R., and Altendorf, K. (1990). Orientation of subunit c of the ATP synthase of Escherichia coli - a study with peptide-specific antibodies. Biochim Biophys Acta 1016, 63-70.